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Updated: Jun 25, 2026

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
Published on: March 9, 2021
Ethnicity and temperature regulation.
Michael I Lambert1, Theresa Mann, Jonathan P Dugas
1MRC/UCT Research Unit of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Newlands, South Africa.
Human populations exhibit clear physical adaptations to diverse global climates. While environmental factors influence traits, genetic differences related to climate adaptation are increasingly being identified.
Area of Science:
- Human adaptation
- Environmental science
- Genetics
Background:
- Global climate diversity creates distinct environmental zones.
- Human populations have adapted lifestyles to these varied climatic conditions.
- Observable phenotypic differences exist between populations in different climates.
Purpose of the Study:
- To explore the interplay between climate, human physiology, and genetics.
- To investigate the genetic basis of climate-driven adaptations.
- To understand how environmental factors influence human morphology and physiology.
Main Methods:
- Comparative analysis of human populations across diverse climatic zones.
- Review of existing literature on climate-induced physiological and morphological changes.
- Examination of gene expression data related to heat and cold exposure.
Main Results:
- Climate significantly influences human characteristics like birth weight, body shape, and skin color.
- Phenotypic differences are evident, but genotypic distinctions are harder to ascertain.
- Over 50 genes show altered expression with heat exposure, and over 20 with cold exposure.
Conclusions:
- Environmental and lifestyle factors contribute to human physiological and morphological variations.
- Genetic origins for more human adaptations to climate are expected as research progresses.
- Further research is needed to fully elucidate the genotypic underpinnings of climate adaptation.
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