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Assessing Whole-Body Lipid-Handling Capacity in Mice
Published on: November 24, 2020
Lipid management in children.
Frances R Zappalla1, Samuel S Gidding
1Nemours Cardiac Center, A. I. DuPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA.
Endocrinology and Metabolism Clinics of North America
|February 17, 2009
Summary
Childhood atherosclerosis necessitates early intervention. Behavioral strategies and, in some cases, medication can mitigate future cardiovascular disease risks in children and adolescents.
Area of Science:
- Pediatrics
- Cardiovascular Medicine
- Public Health
Background:
- Atherosclerosis, a disease of the arteries, originates in childhood.
- The current childhood obesity epidemic poses a significant threat to long-term cardiovascular health.
- Early identification and management of pediatric cardiovascular risk factors are crucial.
Purpose of the Study:
- To highlight the importance of early atherosclerosis prevention in children.
- To discuss the impact of the obesity epidemic on pediatric cardiovascular health.
- To outline therapeutic approaches for pediatric dyslipidemias and multiple risk factors.
Main Methods:
- Review of current literature on pediatric atherosclerosis and cardiovascular risk factors.
- Analysis of the implications of the childhood obesity epidemic.
- Discussion of pharmacologic and behavioral interventions.
Main Results:
- Atherosclerosis development starts in early life.
- Childhood obesity exacerbates cardiovascular disease risk.
- Genetic dyslipidemias and multiple risk factors may necessitate pharmacological treatment.
Conclusions:
- Early behavioral interventions are key to preventing childhood atherosclerosis.
- Addressing the obesity epidemic is vital for pediatric cardiovascular health.
- Pharmacologic therapy should be considered for high-risk pediatric patients.
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