Related Experiment Video

Updated: Jun 25, 2026

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants
12:06

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants

Published on: October 19, 2017

Total synthesis of (-)-amphidinolide K

Haye Min Ko1, Chung Whan Lee, Hyung Kyoo Kwon

  • 1Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea.

Angewandte Chemie (International Ed. in English)
|February 20, 2009
PubMed

Abstract:

Macrolide magic: An enyne cross-metathesis reaction of an alkynyl boronate with an alkene derivative as well as a radical cyclization reaction of a homopropargylic beta-alkoxyacrylate are the key transformations in the total synthesis of the cytotoxic macrolide (-)-amphidinolide K.

More Related Videos

Production and Testing of Antimicrobial Peptides and Their Mimics
10:35

Production and Testing of Antimicrobial Peptides and Their Mimics

Published on: April 10, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

Related Experiment Videos

Last Updated: Jun 25, 2026

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants
12:06

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants

Published on: October 19, 2017

Production and Testing of Antimicrobial Peptides and Their Mimics
10:35

Production and Testing of Antimicrobial Peptides and Their Mimics

Published on: April 10, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

Related Concept Videos

Aldol Condensation with β-Diesters: Knoevenagel Condensation01:27

Aldol Condensation with β-Diesters: Knoevenagel Condensation

The Knoevenagel condensation is an aldol-type reaction involving the condensation of aldehydes or ketones with active methylene compounds such as β-diesters to produce substituted olefins.

Articles linked to this work by shared authors, journal, and citation graph.

Allostatic load profiles, resilience, and psychosocial adaptation in young adults.

Frontiers in psychology·2026

Risk of New-Onset Postoperative Depression After Holmium Laser Enucleation Versus Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia: A Nationwide Retrospective Cohort Study.

Journal of clinical medicine·2026

Shifts in Pediatric Respiratory Virus Trends After the COVID-19 Pandemic: Insights From a 12-Year Hospital-Based Study in South Korea.

International journal of pediatrics·2026

The connection between neonatal jaundice and neurodevelopment later in life: a national birth cohort study.

BMC public health·2026

Prevalence of Immediate-Type Food Allergy and Food-Induced Anaphylaxis in Korean Schoolchildren.

Allergy, asthma & immunology research·2026

Longitudinal trajectories of allergen sensitization in children with different transcriptome profiles from COCOA study.

Allergology international : official journal of the Japanese Society of Allergology·2026

Adaptive Assembly of Dative B←N Frameworks for Dimension-Controlled Hetero-Engineering.

Angewandte Chemie (International ed. in English)·2026

Over 7500 Cycles Achieved in Platinum-Group-Metal-Free Ni-H2 Battery Through Reversible Hydrogen Spillover.

Angewandte Chemie (International ed. in English)·2026

P-Directed and Lewis Acid-Assisted Pd-Catalyzed Si─Me Bond Activation Enabling Alkyl Exchange at Silicon.

Angewandte Chemie (International ed. in English)·2026

Photopatterning Block Copolymer Enables Mechanical Enhancement.

Angewandte Chemie (International ed. in English)·2026

Precise Surgical Navigation of Endometriosis via NIR-II Fluorescence Imaging With a Semiconducting Polymeric Probe.

Angewandte Chemie (International ed. in English)·2026

Amorphous Intermediates Mediate van der Waals Nanosheets Formation via Anion-Exchange-Driven Symmetry Breaking.

Angewandte Chemie (International ed. in English)·2026

Molecular logics in dual sensor regulation of diguanylate cyclase activity-Phosphorylation OR blue-light activation.

Protein science : a publication of the Protein Society·2026

Serendipitous Emergence of Pyrrolo[2,3,4-kl]acridin-1(2H)-one Derivatives: From Unexpected Discovery to Synthetic Development.

Chemical record (New York, N.Y.)·2026

SmI2-mediated tandem cyclization route for stereoselective synthesis of the tetracyclic core of daphenylline.

Organic & biomolecular chemistry·2026

Arylsulfonylaminopyridines as Potential Epac Inhibitors: Design, Synthesis and Effects on Myocardial Strips.

Medicinal chemistry (Shariqah (United Arab Emirates))·2026

Recent Comparative Advances in the Mechanistic Actions and Translational Relevance of Syringic Acid and Vanillic Acid for Oxidative Stress-Associated Disorders.

Recent advances in food, nutrition & agriculture·2026

Herbal Creams in Dermatology: Efficacy, Safety, Formulation, and Regulatory Considerations.

Current pharmaceutical design·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us