Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Interactions: Parasitism01:22

Microbial Interactions: Parasitism

Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Scaling biodiversity conservation through institutional reform.

Conservation biology : the journal of the Society for Conservation Biology·2026
Same author

Is a shortened postoperative albendazole duration after curative surgery for alveolar echinococcosis possible? Results from a prospective multicenter study.

Parasites & vectors·2025
Same author

Optimizing Health Across Humans, Animals, Plants, and Ecosystems: How Long Before Benefits Turn Harmful-and Harm Becomes Healing?

Open forum infectious diseases·2025
Same author

Unexplained subcutaneous swelling: Keep echinococcosis in mind! Report of two primary extrahepatic subcutaneous echinococcosis cases and literature review.

PLoS neglected tropical diseases·2025
Same author

Understanding and Predicting Population Response to Anthropogenic Disturbance: Current Approaches and Novel Opportunities.

Ecology letters·2025
Same author

Epidemiological and clinical characteristics of patients in the alveolar echinococcosis registry, France, 1982 to 2021.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2025
Same journal

[Advances and perspectives in vascularized composite allotransplantation preservation].

Bulletin de l'Academie nationale de medecine·2025
Same journal

[COVID-19: Neurological manifestations and complications during the acute phase of the disease].

Bulletin de l'Academie nationale de medecine·2024
Same journal

[Role of psychological factors in post-COVID-19 condition].

Bulletin de l'Academie nationale de medecine·2023
Same journal

[From the origin of Sars-CoV-2 to dangerous virology/biology].

Bulletin de l'Academie nationale de medecine·2023
Same journal

[Neurological forms of long COVID in adults: Critical approach].

Bulletin de l'Academie nationale de medecine·2023
Same journal

[Post-COVID-19 syndrome].

Bulletin de l'Academie nationale de medecine·2023
See all related articles

Related Experiment Video

Updated: Jun 25, 2026

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies
07:59

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies

Published on: May 31, 2024

[Parasite-host relationships and treatment].

Dominique-Angèle Vuitton1, Georges Mantion, Brigitte Bartholomot

  • 1Centre Collaborateur OMS pour la Prévention et le Traitement des Echinococcoses humaines, Université de Franche-Comté et C.H.U. Jean Minjoz-25030 Besancon.

Bulletin De L'Academie Nationale De Medecine
|February 25, 2009
PubMed
Summary
This summary is machine-generated.

Alveolar echinococcosis (AE) is a parasitic disease caused by Echinococcus multilocularis. Understanding host resistance and parasite tolerance mechanisms, including immune responses and cytokines like IL-10 and TGF-beta, is key for managing this zoonotic disease.

More Related Videos

A Simple Fecal Flotation Method for Diagnosing Zoonotic Nematodes Under Field and Laboratory Conditions
03:46

A Simple Fecal Flotation Method for Diagnosing Zoonotic Nematodes Under Field and Laboratory Conditions

Published on: December 15, 2023

Extracting Venom from the Parasitoid Wasp Trichogramma dendrolimi Using an Artificial Host
03:53

Extracting Venom from the Parasitoid Wasp Trichogramma dendrolimi Using an Artificial Host

Published on: October 6, 2023

Related Experiment Videos

Last Updated: Jun 25, 2026

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies
07:59

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies

Published on: May 31, 2024

A Simple Fecal Flotation Method for Diagnosing Zoonotic Nematodes Under Field and Laboratory Conditions
03:46

A Simple Fecal Flotation Method for Diagnosing Zoonotic Nematodes Under Field and Laboratory Conditions

Published on: December 15, 2023

Extracting Venom from the Parasitoid Wasp Trichogramma dendrolimi Using an Artificial Host
03:53

Extracting Venom from the Parasitoid Wasp Trichogramma dendrolimi Using an Artificial Host

Published on: October 6, 2023

Area of Science:

  • Parasitology
  • Immunology
  • Zoonotic Diseases

Context:

  • Alveolar echinococcosis (AE) is a severe parasitic infection caused by Echinococcus multilocularis.
  • The disease primarily affects the liver and is transmitted through carnivores (like foxes) and contaminated food or contact.
  • Humans act as intermediate hosts, with susceptibility influenced by genetic factors and immune status.

Purpose:

  • To elucidate the complex interplay between the host immune system and Echinococcus multilocularis.
  • To identify mechanisms of parasite tolerance and host resistance in alveolar echinococcosis.
  • To explore potential therapeutic strategies and preventive measures for AE.

Summary:

  • Echinococcus multilocularis larvae cause a tumor-like growth in intermediate hosts, including humans.
  • Host immune responses, involving cytotoxic mechanisms and delayed-type hypersensitivity, normally control parasite growth.
  • Parasite factors (carbohydrate antigens) and host cytokines (IL-10, TGF-beta) contribute to immune tolerance, which can be overcome by interferon-alpha therapy.

Impact:

  • Interferon-alpha shows promise as a therapeutic option for AE patients by rebalancing host immunity.
  • Prevention strategies focus on lifestyle modifications, such as cooking food, deworming domestic animals, and avoiding contact with infected definitive hosts.
  • While vaccination is theoretically possible, practical implementation remains a significant challenge.