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Genomic profiling of breast cancer

Anjita Pandey1, Alok Kumar Singh, Sanjeev Kumar Maurya

  • 1Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.

Journal of Surgical Oncology
|February 25, 2009
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Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...