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Updated: Jun 25, 2026

Identification of Mouse and Human Antibody Repertoires by Next-Generation Sequencing
Published on: March 15, 2019
BEID: database for sequence-structure-function information on antigen-antibody interactions
Joo Chuan Tong1, Chun Meng Song, Paul Thiam Joo Tan
1Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore. jctong@i2r.a-star.edu.sg
Abstract:
The B-cell Epitope Interaction Database (BEID; http://datam.i2r.a-star.edu.sg/BEID) is an open-access database describing sequence-structure-function information on immunoglobulin (Ig)-antigen interactions. The current version of the database contains 164 antigens, 126 Ig and 189 Ig-antigen complexes extracted from the Protein Data Bank (PDB). Each entry is manually verified, classified, and analyzed for intermolecular interactions between antigens and the corresponding bound Ig molecules. Ig-antigen interaction information that is stored in BEID includes solvent accessibility, hydrogen bonds, non-hydrogen bonds, gap volume, gap index, interface area and contact residues. The database can be searched with a user-friendly search tool and schematic diagrams for Ig-antigen interactions are available for download in PDF format. The ultimate purpose of BEID is to enhance the understanding of the rules of engagement between antigen and the corresponding bound Ig molecules. It is also a precious data source for developing computational predictors for B-cell epitopes.
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