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Updated: Jun 25, 2026
03:49
Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System
Published on: September 20, 2018
Questionnaire-based assessment of pelvic organ dysfunction in multiple system atrophy
Tatsuya Yamamoto1, Ryuji Sakakibara, Tomoyuki Uchiyama
1Department of Neurology, Chiba University, Chuo-ku, Chiba, Japan. tatsuya-yamamoto@mbc.nifty.com
Movement Disorders : Official Journal of the Movement Disorder Society
|February 27, 2009
Summary
Pelvic organ dysfunction, including urinary, bowel, and sexual issues, is highly prevalent in multiple system atrophy (MSA) patients. This dysfunction significantly diminishes their quality of life.
Area of Science:
- Neurology
- Urology
- Gastroenterology
Background:
- Multiple system atrophy (MSA) is a neurodegenerative disorder.
- Autonomic dysfunction, particularly urinary symptoms, is a hallmark of MSA.
- Pelvic organ dysfunction significantly impacts the quality of life (QOL) in MSA patients.
Purpose of the Study:
- To determine the prevalence of pelvic organ dysfunction in patients with MSA.
- To assess the impact of this dysfunction on QOL.
Main Methods:
- A questionnaire assessing bladder, bowel, and sexual function was administered to 256 MSA patients and 158 controls.
- Dysfunction severity was categorized (mild, moderate, severe).
- Statistical analysis used the Mann-Whitney U-test.
Main Results:
- MSA patients exhibited significantly higher rates of urinary, bowel, and sexual dysfunction compared to controls.
- Urinary dysfunction affected 70-76% of MSA patients.
- Bowel and sexual dysfunction were also common, impacting QOL.
Conclusions:
- Pelvic organ dysfunction is a common and significant comorbidity in MSA.
- Addressing these dysfunctions is crucial for improving QOL in MSA patients.
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