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A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Allergic contact dermatitis in 136 children patch tested between 2000 and 2006
L Mark Hammonds1, Virginia C Hall, James A Yiannias
1Mayo Clinic, Jacksonville, FL 32224, USA. hammonds.lonnie@mayo.edu
International Journal of Dermatology
|March 6, 2009
Summary
Allergic contact dermatitis patch testing in children reveals a high positive rate, with 61% confirming reactions to allergens like nickel. This highlights the diagnostic value in pediatric cases.
Area of Science:
- Pediatric Dermatology
- Allergy and Immunology
- Contact Dermatitis
Background:
- Allergic contact dermatitis (ACD) is frequently underdiagnosed in children, potentially affecting over 20% of this population.
- Pediatric ACD diagnosis can be challenging, necessitating reliable diagnostic tools.
Purpose of the Study:
- To evaluate the utility and outcomes of patch testing in children suspected of having allergic contact dermatitis.
- To identify common allergens and demographic patterns in pediatric ACD.
Main Methods:
- A retrospective analysis of patch test data was performed.
- The study reviewed records of 136 children (aged 3-18) tested between 2000 and 2006.
- Data included patient demographics, test results, and allergen relevance.
Main Results:
- 61% of pediatric patients tested positive for at least one allergen.
- Nickel, cobalt, gold, and thimerosal were the most frequent allergens.
- Positive test relevance varied, with 53% deemed currently relevant.
- Younger males showed a higher likelihood of positive tests, decreasing with age.
Conclusions:
- Patch testing is a valuable diagnostic tool for children with suspected allergic contact dermatitis, with a high confirmation rate.
- Identifying specific allergens aids in managing pediatric ACD and preventing future exposures.
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