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Published on: September 30, 2014
Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis
Christine M Sedgley1, Don B Clewell, Susan E Flannagan
1Department of Cariology, Restorative Sciences & Endodontics, School of Dentistry, The University of Michigan, 1011 N. University Ave., Ann Arbor, MI 48109-1078, USA. csedgley@umich.edu
Abstract:
The Enterococcus faecalis class IIa bacteriocin MC4-1 encoded by the sex pheromone-responding, multiple-antibiotic resistance plasmid pAMS1 exhibits "siblicidal" (sibling-killing) activity under certain conditions. Stabs of plasmid-containing cells on solid medium containing lawns of bacteria of the same (plasmid-containing) strain give rise to zones of inhibition. If the plasmid-containing host also produces gelatinase, bacteriocin cannot be detected.
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