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Pathophysiology of Vomiting

Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through interaction...
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Related Experiment Video

Updated: Jun 25, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Migraine: a question and answer review.

Randolph W Evans1

  • 1Baylor College of Medicine, Houston, TX 77004, USA. rwevans@pol.net

The Medical Clinics of North America
|March 11, 2009
PubMed
Summary
This summary is machine-generated.

Migraine affects millions annually, and this review covers its epidemiology, causes, and treatments. Both doctors and patients seek improved medication options for better migraine management.

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Related Experiment Videos

Last Updated: Jun 25, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

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05:40

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Published on: July 29, 2021

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05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Area of Science:

  • Neurology
  • Internal Medicine

Background:

  • Migraine impacts over 29 million Americans each year.
  • Internal medicine physicians frequently encounter migraine patients.

Purpose of the Study:

  • To provide a comprehensive review of migraine.
  • To discuss current and desired treatment advancements.

Main Methods:

  • Review of epidemiology
  • Pathophysiology
  • Comorbidity
  • Clinical features
  • Diagnostic testing
  • Acute and preventive treatment
  • Women's issues

Main Results:

  • Migraine is a prevalent condition with significant patient and physician interest in improved therapies.
  • Current treatments and understanding of migraine pathophysiology are evolving.

Conclusions:

  • Further research is needed to develop more effective and tolerable migraine medications.
  • Enhanced understanding and treatment strategies are crucial for managing this widespread neurological disorder.