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Polymorphisms determine beta-adrenoceptor conformation: implications for cardiovascular disease and therapy

Andrea Ahles1, Stefan Engelhardt

  • 1Rudolf Virchow Center, Deutsche Forschungsgemeinschaft Research Center for Experimental Biomedicine, Universitaet Wuerzburg, 97078 Wuerzburg, Germany.

Trends in Pharmacological Sciences
|March 11, 2009
PubMed
Summary

Genetic variations in beta-adrenoceptors influence cardiovascular drug responses. Novel optical methods reveal how these beta-adrenoceptor polymorphisms affect drug efficacy, paving the way for personalized medicine.

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