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Updated: Jun 24, 2026

Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level
11:49

Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level

Published on: November 17, 2013

Oxygen, a paradoxical element?

Maria Greabu1, M Battino, Maria Mohora

  • 1Department of Biochemistry, Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne
|March 17, 2009
PubMed
Summary
This summary is machine-generated.

Oxygen is vital for life but can create harmful reactive oxygen species (ROS). Life evolved antioxidants to combat ROS, though their full impact in the human body remains under investigation.

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Last Updated: Jun 24, 2026

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11:49

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Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Published on: November 8, 2019

Area of Science:

  • Biochemistry
  • Cell Biology
  • Environmental Science

Background:

  • Oxygen is fundamental for terrestrial life.
  • Oxygen's electronic structure can lead to the formation of reactive oxygen species (ROS).
  • ROS pose a threat to biological systems, necessitating antioxidant defenses.

Purpose of the Study:

  • To explore the dual nature of oxygen as essential for life yet capable of producing harmful ROS.
  • To highlight the evolutionary development of antioxidant systems in response to ROS.
  • To underscore the incomplete understanding of oxygen activation consequences in human physiology.

Main Methods:

  • Review of theoretical studies on oxygen's electronic structure.
  • Analysis of experimental data on ROS production.
  • Examination of clinical research on antioxidant functions.

Main Results:

  • Oxygen's essential role in life is balanced by its potential to generate damaging ROS.
  • Antioxidants are crucial biological mechanisms evolved to neutralize ROS.
  • Despite extensive research, the complete physiological impact of oxygen activation is not fully elucidated.

Conclusions:

  • Oxygen presents a paradox: essential for life but a source of cellular damage via ROS.
  • Antioxidant systems are a testament to life's adaptation to oxygen's reactivity.
  • Further research is needed to fully comprehend the implications of oxygen metabolism in human health and disease.