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Related Concept Videos

Quality Assurance01:19

Quality Assurance

Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
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Measurement of Bioavailability: Pharmacodynamic Methods

Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.
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Measurement of Bioavailability: Pharmacokinetic Methods

Pharmacokinetics is a vital branch of pharmacology that examines how drugs are absorbed, distributed, metabolized, and excreted by the body. Two key methodologies in pharmacokinetics are plasma drug concentration studies and urinary drug excretion analyses, both of which provide critical insights into a drug's therapeutic efficacy and bioavailability.Plasma Drug Concentration-Time StudiesPlasma drug concentration-time studies involve analyzing blood samples at specific intervals to quantify...
Pharmaceutical Equivalents01:26

Pharmaceutical Equivalents

As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence01:19

Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence

Pharmaceutical products contain more than just the active drug; they also contain various excipients such as binders, solubilizers, stabilizers, preservatives, and other elements. In some cases, impurities or contaminants might be present. Traditionally, quality control in pharmaceuticals has primarily focused on the analysis of the active drug, often overlooking the impact of these additional components. The recent issue with heparin contamination by over-sulfated chondroitin sulfate, a...
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The acceptance criteria for dissolution profile data are anchored in Q values, representing the percentage of drug dissolved within a specified period. This assessment unfolds in three stages:First Stage: The test passes if all six drug dosage units are equal to or greater than Q plus 5%; otherwise, the sample proceeds to the second stage.Second Stage: The average of twelve units must be equal to or greater than Q, with no unit falling below Q - 15% to pass; if not, it progresses to the final...

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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Published on: August 30, 2018

Measuring pharmacy quality.

David P Nau1

  • 1Competitive Health Analytics, Humana Pharmacy Solutions, Louisville, KY 40202, USA. dnau@humana.com

Journal of the American Pharmacists Association : Japha
|March 18, 2009
PubMed
Summary
This summary is machine-generated.

The healthcare system is shifting to value-based purchasing, emphasizing quality and cost. Pharmacy quality measurement and improvement are crucial for community pharmacies to adapt to these changes.

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Area of Science:

  • Health Services Research
  • Pharmacy Practice
  • Quality Improvement Science

Background:

  • The healthcare system is increasingly focused on value-based purchasing, integrating quality and cost considerations.
  • Community pharmacies are expected to face growing demand for quality and value evidence.
  • The Pharmacy Quality Alliance (PQA) has been established to advance pharmacy quality measurement and improvement.

Purpose of the Study:

  • To outline methods for measuring healthcare quality.
  • To demonstrate the application of these methods to pharmacy quality measurement.
  • To explore strategies for promoting quality improvement in pharmacy practice.

Main Methods:

  • Review of existing healthcare quality measurement methodologies.
  • Analysis of their applicability to the pharmacy sector.
  • Identification of strategies to stimulate adoption of quality improvement practices.

Main Results:

  • Healthcare quality measurement frameworks can be adapted for pharmacy settings.
  • Value-driven healthcare necessitates a focus on pharmacy quality.
  • The PQA is a key initiative for coordinating pharmacy quality efforts.

Conclusions:

  • Pharmacy stakeholders must understand the shift towards value-driven healthcare.
  • Increased demand for pharmacy quality and value evidence is anticipated.
  • Regulatory changes, public reporting, and pay-for-performance models will likely drive quality improvement in pharmacies.