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Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

ScanMoment: a web server for combinatorial analysis of basic residues in nucleic acid binding sites

Steven E Massey1

  • 1Department of Biology, University of Puerto Rico - Rio Piedras, PO Box 23360, San Juan, Puerto Rico 00931. stevenemassey@gmail.com

Bioinformation
|March 19, 2009
PubMed
Abstract

Keywords:
Aspartyl‐tRNA synthetaseFourier transformationalpha helixbasic momentperiodicity

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Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally analyses the...