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Updated: Jun 24, 2026

Standardized Induction and Assessment of Long-term Potentiation-like Cortical Plasticity Using Transcranial Magnetic Stimulation

Standardized Induction and Assessment of Long-term Potentiation-like Cortical Plasticity Using Transcranial Magnetic Stimulation

Published on: November 7, 2025

Evolving trends in induction therapy.

Marta Arias¹, Josep M Campistol, Flavio Vincenti

¹Department of Nephrology and Renal Transplantation, Hospital Clínic, Barcelona, Spain 08036. marias@clinic.ub.es

Transplantation Reviews (Orlando, Fla.)

|March 21, 2009

Summary

This summary is machine-generated.

New biologic agents offer improved safety and efficacy for kidney transplant recipients. These targeted therapies may replace traditional immunosuppressants, reducing long-term toxicity and improving patient outcomes.

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In vitro Induction of Human Dental Pulp Stem Cells Toward Pancreatic Lineages

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Published on: September 25, 2021

Area of Science:

Nephrology
Immunology
Pharmacology

Background:

Maintenance immunosuppressive drugs have significantly reduced acute rejection and improved transplant outcomes.
Current immunosuppressants often lack specificity, require frequent monitoring, and carry acute and chronic toxicities.

Purpose of the Study:

To evaluate the potential of novel biologic agents as safer alternatives in renal transplantation.
To compare the toxicity profiles of biologic agents versus traditional oral maintenance drugs.

Main Methods:

Review of recent innovations in immunosuppressive drug development for renal transplantation.
Analysis of the characteristics, efficacy, and toxicity of new biologic agents (monoclonal antibodies, receptor-fusion proteins).

Main Results:

New biologic agents demonstrate minimal toxicity due to targeted action.
These agents have long half-lives, allowing intermittent administration.
Biologic agents show potential for reduced long-term toxicity compared to corticosteroids and calcineurin inhibitors.

Conclusions:

Novel biologic agents represent a significant advancement in immunosuppression post-renal transplantation.
Targeted biologic therapies may offer a safer alternative, potentially replacing conventional drugs associated with long-term side effects.