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Updated: Jun 24, 2026

Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia
Published on: November 9, 2018
Cerebral MRI lesions and anti-tumor necrosis factor-alpha therapy
Alexander Winkelmann1, Robert Patejdl, Sabine Wagner
1Department of Neurology, University of Rostock, Gehlsheimer Strasse 20, 18147 Rostock, Germany. alexander.winkelmann@med.uni-rostock.de
Abstract:
We discuss two cases receiving different anti-tumornecrosis-factor alpha antagonists (anti-TNF-alpha); one for psoriatic arthritis (PA) and the other for ankylosing spondylitis (AS). Due to neurological symptoms cerebral magnetic resonance imaging (MRI) was performed and cerebral lesions were detected. Our interpretations of these cerebral lesions and the resulting diagnostic and therapeutic consequences are presented in regard of data published in the medical literature.

