Related Experiment Video
Updated: Jun 24, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Hereditary sensory and autonomic neuropathy type IV orthopaedic complications
Ivo Marik1, Miroslav Kuklik, Dana Kuklikova
1Ambulant Centre for Defects of Locomotor Apparatus, Praha, Czech Republic.
Abstract:
Painless fractures with delayed healing or abnormal callus formation require exclusion of a systemic disorder. We report a 9-year-old girl with hereditary sensory and autonomic neuropathy type IV who developed bone changes in the hind foot after a protracted healing of a tibia fracture. Osteomyelitis was considered as a possible cause of destruction of the tarsal bones. Negative sweat test documented anhydrosis. Late diagnosis in our patient occurred because of an unusual clinical course of the disease.
Related Concept Videos
Diabetic Neuropathy
Peripheral Artery Disease IV: Nursing Management
Spinal Cord Injury ll: Pathophysiology
Secondary Spinal Cord Injury llI: Pathophysiology
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation