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Transport evaluation of alendronate across Caco-2 cell monolayers

F Karamustafa1, N Celebi, Z Değim

  • 1Department of Pharmaceutical Technology, Gazi University, Faculty of Pharmacy, Etiler, Ankara, Turkey.

Die Pharmazie
|March 27, 2009
PubMed
Summary

Dimethyl-beta-cyclodextrin (DM-beta-CD) significantly enhances alendronate transport across Caco-2 cell monolayers. This study identified optimal non-toxic concentrations for alendronate and enhancers, suggesting DM-beta-CD

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