Related Experiment Video
Updated: Jun 24, 2026
08:49
Propagating and Detecting an Infectious Molecular Clone of Maedi-visna Virus that Expresses Green Fluorescent Protein
Published on: October 9, 2011
[Kawasaki disease in Iceland 1979-1997.]
Laeknabladid
|March 27, 2009
Summary
Kawasaki disease, a serious inflammatory condition in children, affects 8.5 per 100,000 annually in Iceland. Early treatment with intravenous immunoglobulins improved outcomes, with low rates of coronary aneurysms.
Area of Science:
- Pediatric Rheumatology
- Infectious Diseases
- Cardiology
Context:
- Kawasaki disease is a critical multisystem inflammatory illness primarily impacting young children.
- The initial documented case in Iceland occurred in 1979, necessitating a review of the disease's prevalence and characteristics.
- This study examines 19 years of Kawasaki disease cases in Iceland, from 1979 to 1997.
Purpose:
- To retrospectively analyze the incidence, clinical features, and management of Kawasaki disease in Iceland.
- To assess the occurrence of coronary artery abnormalities and treatment outcomes.
- To compare Icelandic incidence rates with other Nordic countries.
Summary:
- A total of 40 children were diagnosed with Kawasaki disease between 1979 and 1997, yielding an annual incidence of 8.5 per 100,000 children under five.
- The male-to-female ratio was 2:1. Coronary aneurysms were identified in 13% of patients who underwent echocardiography, and one patient (2.5%) died from cardiac complications.
- Treatment with intravenous immunoglobulins was administered to 90% of patients diagnosed after 1987, with favorable results.
Impact:
- The incidence in Iceland aligns with rates reported in other Nordic nations, suggesting similar environmental or genetic factors.
- The study highlights the importance of timely diagnosis and treatment, particularly with intravenous immunoglobulins, to mitigate cardiac sequelae.
- Findings provide valuable epidemiological data for public health planning and further research into Kawasaki disease.
Related Concept Videos
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
01:28Infectious Diseases and Their Occurrence
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
01:23Rheumatic Heart Disease I: Introduction
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
01:30Inflammatory Bowel Disease II: Crohn's Disease
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
01:27Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...