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Updated: Jun 24, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Carotid plaque in absence of traditional and non-traditional cardiovascular risk factors

Pyung Chun Oh, Seung Hwan Han, Ju Seung Kim

    International Journal of Cardiology
    |March 28, 2009
    PubMed

    Insights

    Carotid plaque, a marker of atherosclerosis, can indicate coronary artery disease. This case highlights potential unknown factors contributing to carotid plaque development, even without typical cardiovascular risk factors.

    Area of Science:

    • Cardiovascular Medicine
    • Atherosclerosis Research
    • Diagnostic Imaging

    Background:

    • Carotid plaque signifies subclinical atherosclerosis, predicting coronary artery disease and cardiovascular events.
    • Atherosclerosis is a major cause of cardiovascular morbidity and mortality worldwide.
    • Early detection of atherosclerosis is crucial for timely intervention.

    Observation:

    • A patient presented with chest discomfort and ECG abnormalities.
    • Treadmill testing showed horizontal ST segment depression.
    • Coronary angiography revealed no significant coronary artery stenosis.

    Findings:

    • Carotid ultrasonography detected carotid plaque.
    • The patient had no traditional or non-traditional cardiovascular risk factors, including normal lipid profiles.
    • This suggests atherosclerosis can develop independently of common risk factors.

    Implications:

    • Unknown determinants may drive carotid plaque formation and atherosclerosis.
    • Further research is needed to identify novel risk factors for atherosclerosis.
    • This case underscores the complexity of atherosclerosis and the need for comprehensive diagnostic approaches.

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