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Updated: Aug 18, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
[Immunoregulating phenomena in patients with alcoholic cirrhosis]
B Esparza Echevarría1, B de las Heras Niño, D Solano López
1Universidad del País Vasco/Euskal Herriko Unibertsitatea, Facultad de Medicina, Departamento de Medicina, Lejona, Vizcaya.
Abstract:
Several immunologic changes, both humoral and cellular, have been described in patients with post-alcoholic cirrhosis. One of these changes was a polyclonal hypergammaglobulinemia which can be produced by a failure in the immunoregulation dynamics. The number of leukocytes, as well as lymphocytic population and subpopulation, did not prove significant differences between healthy people and patients. The seric immunoglobulin showed an increase of IgG in cirrhotics. The synthesis of immunoglobulins "in vitro" showed increased productions in cirrhotics; this being spontaneous in IgA and induced by pokeweed in the case of IgG and IgA.
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