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Updated: Jun 24, 2026

Orthotopic Small Bowel Transplantation in Rats
Published on: November 6, 2012
Non-anatomical intestinal transplantation
R Charco1, C Malagelada, L Llopart
1Service of Hepatobiliopancreatic and Transplantation Surgery, Unit of Nutritional Support, University Hospital Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, Spain. rcharco@vhebron.net
Introduction:
Intestinal transplantation is the only long-range treatment option for patients with intestinal failure. We report an exceptional case of isolated intestinal transplantation with the implant in a non-anatomical position.
Clinical Case:
The patient was a thirty-eight-year-old man (60 kg weight, 180 cm height, 18.3 body mass index) with intestinal failure and home parenteral nutrition due to a short-bowel syndrome for which intestinal transplantation was indicated. The patient had a vascular malformation with the cava vein located left to the aorta, and the intestine was implanted with a 180 masculine rotation around the mesenteric axis, so that the implant s superior mesenteric artery and vein matched the recipient s cava and aorta. Postoperative follow-up was excellent and the patient was discharged after six weeks with a 10-kg gain in body weight.
Discussion:
This non-anatomical intestinal implantation of the small bowel, previously unreported, offers technical advantages over other options. Adequate intestinal function represents a unique model to prove the viability of intestinal implants in a non-anatomical position.
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