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Profiling Thiol Redox Proteome Using Isotope Tagging Mass Spectrometry
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Electrochemically initiated tagging of thiols using an electrospray ionization based liquid microjunction surface

Gary J Van Berkel1, Vilmos Kertesz

  • 1Organic and Biological Mass Spectrometry Group, Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6131, USA. vanberkelgj@ornl.gov

Rapid Communications in Mass Spectrometry : RCM
|April 2, 2009
PubMed
Summary

This study converted a liquid microjunction surface sampling probe (LMJ-SSP) into an electrochemical cell for analyte tagging. This novel electrochemical surface sampling method achieved efficient peptide cysteine tagging with hydroquinone tags.

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