Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Oxylipins from Dracontium loretense.

Angelyne Benavides¹, Assunta Napolitano, Carla Bassarello

¹Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, SA, Italy.

Journal of Natural Products

|April 4, 2009

Summary

Four new oxylipins were discovered in the Dracontium loretense plant. One oxylipin demonstrated an immunostimulatory effect on human peripheral blood mononuclear cells (PBMC) proliferation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

<i>Cucurbita pepo</i> var. <i>styriaca</i> Seeds: Deep Insights into Polar Lipid Profile.

Foods (Basel, Switzerland)·2026

Same author

Chemical Profile and Evaluation of the Growth-Inhibitory, Anti-Inflammatory, and Antioxidant Activity Potential of Polar Extracts of <i>Reseda alba</i> L. (Resedaceae).

Plants (Basel, Switzerland)·2026

Same author

PRDM Proteins Orchestrate Colorectal Cancer Tumorigenesis.

International journal of molecular sciences·2026

Same author

Guaiane-type sesquiterpenes from Carciofo Bianco di Pertosa, a cultivar of Cynara cardunculus subsp. scolymus (L.), leaf: Isolation and evaluation of tyrosinase inhibitory activity.

Fitoterapia·2026

Same author

Gold Nanoparticles Enhance Radiosensitivity in Glioblastoma Cells.

ACS omega·2026

Same author

PRDM players in central nervous system cancers: State of the art and future perspectives.

Critical reviews in oncology/hematology·2026

Area of Science:

Natural Product Chemistry
Medicinal Chemistry
Immunology

Background:

Dracontium loretense is a plant species with potential medicinal properties.
Oxylipins are a class of compounds derived from fatty acids, often exhibiting biological activity.

Purpose of the Study:

To isolate and characterize novel oxylipins from Dracontium loretense.
To evaluate the biological activity of the isolated oxylipins, specifically their effect on immune cells.

Main Methods:

Extraction of compounds from Dracontium loretense corms using n-butanol.
Structure elucidation using 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy.
Mass spectrometry analysis, including electrospray ionization multistage ion trap mass spectrometry (ESI-ITMS(n)).

More Related Videos

Dissection and Lipid Droplet Staining of Oenocytes in Drosophila Larvae

Dissection and Lipid Droplet Staining of Oenocytes in Drosophila Larvae

Published on: December 28, 2019

Related Experiment Videos

Last Updated: Jun 24, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Dissection and Lipid Droplet Staining of Oenocytes in Drosophila Larvae

Dissection and Lipid Droplet Staining of Oenocytes in Drosophila Larvae

Published on: December 28, 2019

Determination of relative configurations using coupling constants and Nuclear Overhauser Effect (ROE) data.

Main Results:

Four novel oxylipins, designated 1-4, were successfully isolated and their structures determined.
Oxylipin 2 was found to possess an immunostimulatory effect, promoting the proliferation of human peripheral blood mononuclear cells (PBMC).

Conclusions:

The study successfully identified new oxylipin compounds from Dracontium loretense.
Oxylipin 2 shows promise as an immunostimulant, warranting further investigation for therapeutic potential.