Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Compact Quantum Dots for Single-molecule Imaging

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

Beta-cyclodextrin-modified CdSe/ZnS quantum dots for sensing and chiroselective analysis.

Ronit Freeman¹, Tali Finder, Lily Bahshi

¹Institute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

|April 10, 2009

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Redox- and Photo-Responsive Fe<sup>3+/2+</sup>-Cross-Linked Carboxymethyl Cellulose Methacrylate Dissipative Gels: Synthesis and Applications.

ACS applied materials & interfaces·2026

Same author

Intracellular logic computing with DNA tetrahedron processors enables precision cancer theranostics.

Signal transduction and targeted therapy·2026

Same author

Dictated cell adhesion and migration using microfluidic-controlled synthetic hydrogels exhibiting programmable viscoelasticities.

Journal of materials chemistry. B·2026

Same author

Photoactivated Signaling Networks using DNA-Based Synthetic Organelles as Biomimetic Protocells.

Angewandte Chemie (International ed. in English)·2026

Same author

Dynamic Switchable and Transient DNA Condensates Driven by Aptamer-Ligand or Ion-Nucleobase Bridged Complexes.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same author

Allosteric ligand-aptamer complexes orchestrate supramolecular or transient catalytic, transcription and fibrinogenesis processes.

Chemical science·2026

Same journal

Intrinsic Superconducting Gap in Bilayer KCa<sub>2</sub>Fe<sub>4</sub>As<sub>4</sub>F<sub>2</sub> and Decoupled Monolayer FeAs.

Nano letters·2026

Same journal

Programmable Hydrogen-Assisted Chemical Vapor Deposition Growth and Bipolar Transport in Two-Dimensional MoO<sub>2</sub> Nanoflakes.

Nano letters·2026

Same journal

A Curvature-Modulated Strategy for Single-Atom Catalysts toward Reciprocal Regulation in Li-S Batteries.

Nano letters·2026

Same journal

Vacuum Pyrolysis Engineered CoSb/C Scaffold for Sodium Metal Anodes with Sodiophilic and Superionic Interphase.

Nano letters·2026

Same journal

Hexagonal SiGe Quantum Dots in Nanowires.

Nano letters·2026

Same journal

Monolithic Axial InGaAs Quantum Dot Emitters in GaAs-Based Nanowires via Sb-Mediated Facet Engineering.

Nano letters·2026

See all related articles

Beta-cyclodextrin functionalized quantum dots enable sensitive optical sensing. These nanomaterials achieve chiroselective sensing and competitive analysis via fluorescence resonance energy transfer and electron transfer mechanisms.

Area of Science:

Nanomaterials Science
Analytical Chemistry
Biochemistry

Background:

Quantum dots (QDs) offer unique optical properties for sensing applications.
Beta-cyclodextrin (beta-CD) is a versatile host molecule for molecular recognition.
Combining QDs with beta-CD enhances sensing capabilities through tailored interactions.

Purpose of the Study:

To develop beta-cyclodextrin-functionalized CdSe/ZnS quantum dots for advanced optical sensing.
To explore fluorescence resonance energy transfer (FRET) and electron transfer (ET) mechanisms for substrate detection.
To demonstrate chiroselective sensing and competitive analysis using these modified QDs.

Main Methods:

Synthesis of beta-cyclodextrin-functionalized CdSe/ZnS quantum dots.

More Related Videos

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads

Published on: June 28, 2024

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

Related Experiment Videos

Last Updated: Jun 24, 2026

Compact Quantum Dots for Single-molecule Imaging

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads

Published on: June 28, 2024

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

Utilizing FRET between QDs and Rhodamine B for competitive assays.

Employing ET quenching for optical detection of specific analytes.

Implementing chiroselective optical discrimination of amino acids.

Main Results:

Successful application of FRET for competitive analysis of adamantanecarboxylic acid and p-hydroxytoluene.
Demonstrated chiroselective optical discrimination between D,L-phenylalanine and D,L-tyrosine.
Effective optical detection of p-nitrophenol via an ET quenching pathway.

Conclusions:

Beta-cyclodextrin-functionalized QDs are effective platforms for diverse optical sensing strategies.
The FRET and ET mechanisms provide sensitive and selective detection routes.
These QD-based sensors show promise for both chemical and biological analyses.