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P-wave dispersion and P-wave duration in children with stable asthma bronchiale
Oya Yücel1, Mustafa Yildiz, Sevin Altinkaynak
1Department of Pediatrics, Sakarya University, Sakarya, Turkey. oyayucel2000@yahoo.com
Insights
P-wave dispersion, a measure of sinus impulse propagation, was studied in children with stable asthma. Results showed a correlation between P-wave dispersion and anthropometric factors like age, weight, and height in these children.
Area of Science:
- Pediatric Cardiology
- Respiratory Medicine
- Electrophysiology
Background:
- P-wave dispersion reflects sinus impulse propagation heterogeneity.
- Asthma can affect cardiac electrical activity.
- Understanding these effects in children is crucial for comprehensive care.
Purpose of the Study:
- To investigate P-wave dispersion in children with stable asthma.
- To compare P-wave dispersion between asthmatic children and healthy controls.
- To identify potential correlations between P-wave dispersion and clinical parameters.
Main Methods:
- Cross-sectional study involving 20 children with stable asthma and 20 healthy controls.
- P-wave duration measured via 12-lead surface electrocardiography.
- P-wave dispersion calculated as the difference between maximum and minimum P-wave durations.
Main Results:
- P-wave maximum duration was slightly increased in asthmatic children (0.092 ± 0.017 ms) versus controls (0.083 ± 0.011 ms), though not statistically significant (p=0.07).
- Significant correlations were found between P-wave dispersion and age (r=0.40, p=0.01), weight (r=0.41, p=0.008), and height (r=0.41, p=0.008).
Conclusions:
- P-wave maximum duration shows a slight increase in children with stable asthma.
- P-wave dispersion is significantly correlated with age, weight, and height in this pediatric asthma cohort.
Objective:
P-wave dispersion is associated with inhomogeneous and discontinuous propagation of sinus impulses. The aim of this present study was to investigate the impact of P-wave dispersion in children with stable asthma.
Methods:
In this cross-sectional study, the study group consisted of 20 children (12 boys, 8 girls) with stable asthma and mean age of 7.7 +/- 2.0 years. During the study, these patients were treated with low dose inhaled corticosteroids for at least six months. Control group consisted of 20 healthy children matched by same sex and age population. Age, weight, height, echocardiographic values, P-wave maximum duration and P-wave dispersion were compared between asthmatic and healthy children. P-wave duration was calculated in 12-leads of the surface electrocardiography. The difference between P maximum and P minimum durations was defined as P-wave dispersion. The obtained results were compared by independent samples t test and Mann-Whitney U test. Correlations for P-wave dispersion were calculated using Pearson test.
Results:
P-wave maximum duration is slightly increased in patients with stable asthma (0.092 +/- 0.017 ms) as compared with healthy controls (0.083 +/- 0.011 ms) (p=0.07). We found significant correlation between P-wave dispersion and age (r=0.40, p=0.01), weight (r=0.41, p=0.008) and height (r=0.41, p=0.008).
Conclusion:
P-wave maximum duration is slightly increased and P-wave dispersion is correlated with age, weight and height in children with stable asthma.
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