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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: Jun 24, 2026

Modeling Cataract Surgery in Mice
05:19

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

[Cataract surgery without preoperative mydriasis].

K Maresová1, J Procházková

  • 1Ocní klinika LF UP a FN, Olomouc. maresovk@fnol.cz

Ceska a Slovenska Oftalmologie : Casopis Ceske Oftalmologicke Spolecnosti a Slovenske Oftalmologicke Spolecnosti
|April 16, 2009
PubMed
Summary

Intracameral lidocaine effectively achieves preoperative mydriasis during cataract surgery, offering a safe alternative to traditional eye drops. This method reduces preparation time and potential adverse effects for patients.

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Pharmacology

Context:

  • Traditional preoperative mydriasis relies on topical sympathomimetics and parasympatholytics.
  • These standard methods present drawbacks including prolonged preparation, ocular toxicity, and systemic side effects.

Purpose:

  • To evaluate the efficacy and safety of intracameral lidocaine 1% for achieving mydriasis during cataract surgery.
  • To present an alternative to conventional mydriatic eye drops.

Summary:

  • The study involved 33 patients (38 eyes) undergoing cataract surgery with intracameral lidocaine for mydriasis.
  • Mean pupil diameter increased from 3.04 mm to 7.11 mm within 8.82 seconds.
  • The mydriatic effect was found to be adequate, long-lasting, and the procedure was deemed safe.

Impact:

  • Intracameral lidocaine provides a safe and effective alternative for intraoperative mydriasis in cataract surgery.
  • This approach may streamline surgical preparation and minimize patient-related adverse events associated with topical mydriatics.