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Trees from trees: construction of phylogenetic supertrees using clann
Christopher J Creevey1, James O McInerney
1EMBL Heidelberg, Heidelberg, Germany.
Methods in Molecular Biology (Clifton, N.J.)
|April 21, 2009
Summary
Supertree methods integrate diverse phylogenetic trees, even with partial data overlap, to resolve complex evolutionary questions. This study details the widely used "clann" software for constructing these supertrees.
Area of Science:
- Phylogenetics and Evolutionary Biology
- Computational Biology
- Bioinformatics
Background:
- Phylogenetic trees are crucial for understanding evolutionary relationships but are often limited by data availability or computational complexity.
- Combining information from disparate sources (e.g., molecular and morphological data) or partially overlapping datasets presents a significant challenge in phylogenetics.
- Supertree methods offer a powerful approach to synthesize multiple phylogenetic trees, overcoming limitations of individual datasets and computational intractability.
Purpose of the Study:
- To introduce and explain supertree methods for reconstructing a comprehensive phylogenetic tree from multiple sources.
- To demonstrate the utility of supertree approaches in addressing long-standing phylogenetic challenges.
- To provide a practical guide for using the 'clann' software for supertree construction.
Main Methods:
- Description of widely used supertree methodologies.
- Step-by-step tutorial for using the 'clann' software.
- Utilizing 'clann' for investigating phylogenetic information and reconstructing supertrees.
Main Results:
- Supertree methods enable the integration of phylogenetic information from datasets with partial overlaps and diverse data types.
- The 'clann' software provides a user-friendly platform for implementing these supertree methods.
- Application of supertree approaches can illuminate previously intractable phylogenetic problems.
Conclusions:
- Supertree methods, particularly as implemented in 'clann', are effective tools for synthesizing phylogenetic data.
- The software facilitates the reconstruction of robust phylogenetic trees, aiding in resolving evolutionary conundrums.
- 'clann' is a valuable, freely available resource for the bioinformatics and evolutionary biology communities.
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