Paclitaxel-induced ST-segment elevations
Gökmen Gemici1, Altuğ Cinçin, Muzaffer Değertekin
1Yeditepe University Hospital, Istanbul, Turkey. kardiyolog@ttnet.net.tr
Abstract:
A 51-year-old woman presented with severe chest pain minutes after starting intravenous paclitaxel as a part of the systemic chemotherapy due to ovarian carcinoma. The electrocardiogram (ECG) revealed sinus rhythm with ST-segment elevations in inferior and anterior leads. The ST-segment elevations resolved immediately after sublingual nitroglycerine. Cardiac troponin T and CPK MB levels remained in the normal range at repeat measurements. It was presumed that in spite of standard premedication, paclitaxel had induced acute coronary syndrome with ST-segment elevations in this patient.
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