ECD cotton effect approximated by the Gaussian curve and other methods
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Updated: Jun 23, 2026

Methodology for Developing Life Tables for Sessile Insects in the Field Using the Whitefly, Bemisia tabaci, in Cotton As a Model System
Published on: November 1, 2017
Philip J Stephens1, Nobuyuki Harada
1Department of Chemistry, University of Southern California, Los Angeles, California, USA.
Abstract:
To determine the absolute configuration of chiral compounds, theoretical calculations of ECD spectra have been extensively carried out, where the shape of component CD Cotton effects was approximated by the Gaussian distribution curve. However, in some articles, errors are found in the equations of Gaussian curve expressing CD Cotton effects. In this short review, the correct and general forms of the Gaussian equation and the approximation of the CD curve by other methods are described.
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