A gain criterion for the improvement of detection tasks with sub-Poissonian light

Julien Fade1, Philippe Réfrégier, Nicolas Treps

  • 1Institut Fresnel, CNRS, Aix-Marseille Université, Ecole Centrale Marseille, Campus de Saint-Jérôme, 13013 Marseille, France.

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Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...