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Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...

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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
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Decreasing perinatal mortality in The Netherlands, 2000-2006: a record linkage study.

A C J Ravelli1, M Tromp, M van Huis

  • 1Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands. a.c.ravelli@amc.uva.nl

Journal of Epidemiology and Community Health
|May 7, 2009
PubMed
Summary
This summary is machine-generated.

Dutch perinatal mortality decreased from 2000-2006, with significant declines observed across most risk groups. However, overall levels remain high compared to European benchmarks, indicating ongoing challenges in reducing infant and fetal mortality rates.

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Published on: December 31, 2015

Area of Science:

  • Perinatal health research
  • Public health surveillance
  • Epidemiology

Background:

  • Previous studies indicated higher perinatal mortality in The Netherlands compared to other European nations.
  • This study aimed to analyze recent trends and influencing risk factors in Dutch perinatal mortality.

Purpose of the Study:

  • To investigate the trend in perinatal mortality in The Netherlands between 2000 and 2006.
  • To identify the impact of various risk factors on this trend.

Main Methods:

  • A retrospective cohort study analyzed 1,246,440 singleton births from 2000-2006.
  • Data were linked from midwifery, obstetrics, and neonatology registries.
  • Perinatal mortality (fetal and early neonatal) was the primary outcome measure, with trend analysis performed with and without risk adjustment.

Main Results:

  • A significant decline in perinatal mortality was observed, from 10.5 to 9.1 per 1000 births.
  • This downward trend persisted after risk adjustment and was evident in both fetal and neonatal mortality.
  • The decline was most notable in births with congenital anomalies, premature births (32.0-36.6 weeks), and term births; home births had the lowest mortality risk.

Conclusions:

  • Dutch perinatal mortality showed a steady decline between 2000-2006, independent of known risk factors like advanced maternal age or non-western ethnicity.
  • The reduction was observed across most risk groups, excluding very premature births.
  • Despite the decline, Dutch perinatal mortality rates remain comparatively high by European standards.