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Types I and II interferons upregulate the costimulatory CD80 molecule in monocytes via interferon regulatory factor-1

B Bauvois1, J Nguyen, R Tang

  • 1INSERM, U872, Paris F-75006, France. brigitte.bauvois@crc.jussieu.fr

Biochemical Pharmacology
|May 13, 2009
PubMed
Summary

Interferons (IFNs) boost CD80 expression on monocytes, crucial for T cell immunity. This upregulation, mediated by interferon regulatory factors (IRFs), may help predict patient response to cancer immunotherapies.

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