Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Holographic tomographic volumetric additive manufacturing.

Nature communications·2025

Same author

HoloTile light engine: new digital holographic modalities and applications.

Reports on progress in physics. Physical Society (Great Britain)·2024

Same author

Phase-only steerable photonic nanojets.

Optics express·2023

Same author

Holographic microscope and its biological application.

Neuroscience research·2021

Same author

Optical catapulting of microspheres in mucus models-toward overcoming the mucus biobarrier.

Journal of biomedical optics·2019

Same author

Light-driven micro-tool equipped with a syringe function.

Light, science & applications·2018

Same journal

Denoising algorithm of Φ-OTDR systems based on adaptive fractional wavelet transform denoising.

Optics express·2026

Same journal

Millisecond photon-to-photon latency and high-speed volumetric projection system for optogenetics.

Optics express·2026

Same journal

Polarization-encoded coaxial structured light for high-precision 3D surface profilometry.

Optics express·2026

Same journal

Discrete freeform optical design based on collaborative optimization of point cloud and local normals.

Optics express·2026

Same journal

Ultrafast ghost imaging with 25 GHz speckle switching and wavelength-division multiplexing.

Optics express·2026

Same journal

Atomic vapor cells fabricated by femtosecond laser welding of standard-optical-quality glass.

Optics express·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Published on: October 13, 2011

Fully dynamic multiple-beam optical tweezers.

Rene Eriksen, Vincent Daria, Jesper Gluckstad

|May 14, 2009

Summary

This summary is machine-generated.

We developed a new method for creating dynamic optical tweezers using generalized phase contrast and a spatial light modulator. This technique allows for real-time control over multiple optical traps for precise manipulation.

More Related Videos

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution

Published on: May 27, 2013

Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

Published on: November 2, 2018

Related Experiment Videos

Last Updated: Jun 23, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Published on: October 13, 2011

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution

Published on: May 27, 2013

Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

Published on: November 2, 2018

Area of Science:

Optics and Photonics
Biophysics
Microscopy and Imaging

Background:

Optical tweezers are crucial tools for manipulating microscopic objects.
Existing methods for generating multiple optical traps can be complex and limited in dynamic control.

Purpose of the Study:

To demonstrate a novel technique for generating fully dynamic multiple-beam optical tweezers.
To enable real-time, adaptable control over optical trap arrays.

Main Methods:

Utilized the generalized phase contrast (GPC) method.
Employed a phase-only spatial light modulator (SLM) to shape optical beams.
Developed a straightforward process for transforming phase patterns into optical traps.

Main Results:

Successfully generated an adjustable array of high-intensity beams acting as optical traps.
Achieved real-time control over the position, size, shape, and intensity of individual optical tweezers.
Demonstrated the trapping and dynamic manipulation of multiple micro-spheres in a liquid solution.

Conclusions:

The GPC method combined with an SLM offers a flexible and efficient approach for creating dynamic multiple-beam optical tweezers.
This technique provides precise control over optical trap arrays, advancing capabilities in micro-manipulation.