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Updated: Jun 23, 2026
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Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins
Published on: August 7, 2014
Quantitation of biomolecules conjugated to nanoparticles by enzyme hydrolysis
Fiona McKenzie1, Victoria Steven, Andrew Ingram
1Centre for Molecular Nanometrology, WestCHEM, Pure and Applied Chemistry, University of Strathclyde, Glasgow, UK.
Chemical Communications (Cambridge, England)
|May 14, 2009
Abstract:
A novel method for quantifying biomolecules immobilised onto gold and silver nanoparticles is reported; fluorescent-labelled antibodies and DNA are hydrolysed on the surface of the nanoparticles by the addition of trypsin and DNase I, respectively, resulting in the release of the quantifiable fluorescent label into the bulk solution.
