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Updated: Jan 20, 2026
Gold Nanoparticle Synthesis
Published on: July 10, 2021
Facile preparation of gold nanoparticles-liposome composites
Toshio Sakai1, Tsubasa Mukawa, Koji Tsuchiya
1Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba 278-8510, Japan.
Abstract:
We report here facile preparation of gold nanoparticles-liposome composites (AuNPs-liposome) in aqueous solutions at ambient conditions in the absence of any reducing agents and energy input. The AuNPs-liposomes were prepared by simply mixing of an aqueous solution of hydrogen tetrachloroaureate (III) hydrate (HAuCl4.3H2O) and a dispersion of poly(ethylene glycol)-grafted liposomes (PEG-liposomes) that are comprised of distearoyl-N-monomethyoxy poly(ethylene glycol)-succinyl-phosphatidylethanoamine (DSPE-PEG) and L-alpha-dipalmitoylphosphatidylcholine (DPPC). The AuNPs-liposomes formed consist of a liposome (with diameter of 50-200 nm) combining with a AuNP (with diameter of 30-50 nm).
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