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Related Concept Videos

The Structure of Intermediate Filaments01:19

The Structure of Intermediate Filaments

The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of microfilaments (7 nm) and the microtubules (25 nm).  These filaments are highly stable and can remain intact when exposed to high salt concentrations and detergents. These filaments are responsible for providing stability and mechanical support to the cells. They also help in cell adhesion and maintaining tissue integrity.
Intermediate filaments...
Types of Intermediate Filaments01:31

Types of Intermediate Filaments

The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and II are acidic and basic keratin proteins. Type III is of mesodermal origin and comprises four proteins: vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Vimentin is commonly found in mesenchymal cells, desmin in muscle cells, GFAP in astrocytes, while peripherin is found in peripheral nervous system neurons (PNS). Type...
Fibrous Proteins00:55

Fibrous Proteins

Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...
Fiber Reinforced Concrete01:22

Fiber Reinforced Concrete

Fiber-reinforced concrete significantly enhances the structural and nonstructural properties of traditional concrete by incorporating fibers like steel, glass, and polymers. These fibers, varying from natural ones such as sisal and cellulose to manufactured ones like polypropylene and Kevlar, are mixed into hydraulic cement with aggregates. Steel fibers, often preferred for their robustness, contribute to improved ductility, toughness, and post-cracking performance. The concrete is classified...
Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
Disassembly of Intermediate Filaments01:35

Disassembly of Intermediate Filaments

Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to regulate their disassembly. The IF concentration in the cytoplasm also regulates the disassembly. If the concentration crosses a threshold, it activates the protein kinases in the vicinity, allowing the phosphorylation of IFs.
Keratin proteins, found at the cell periphery near cell junctions, undergo a cycle of assembly and disassembly. In Type...

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Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
07:38

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Published on: January 8, 2014

Linear-core-array microstructured fiber.

Libo Yuan1, Qiang Dai, Fengjun Tian

  • 1Photonics Research Center, College of Science, Harbin Engineering University, Harbin 150001, China. lbyuan@vip.sina.com

Optics Letters
|May 19, 2009
PubMed
Summary
This summary is machine-generated.

Researchers developed linear-core-array microstructured fibers for high-power fiber lasers. These fibers enhance laser beam shape and quality by controlling supermode propagation.

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Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
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Area of Science:

  • Optical Fiber Technology
  • Photonics
  • Materials Science

Background:

  • Microstructured fibers offer unique light-guiding properties.
  • Controlling light propagation in multi-core fibers is crucial for advanced laser applications.

Purpose of the Study:

  • To fabricate and investigate linear-core-array microstructured fibers.
  • To analyze the supermode propagation and coupling characteristics.
  • To assess the potential for improving high-power fiber laser beams.

Main Methods:

  • Modified chemical-vapor deposition and etching for core fabrication.
  • Stacking of D-shape large-scale silica rods for fiber preform.
  • Coupled-mode theory for supermode analysis.

Main Results:

  • Successful fabrication of linear-core-array microstructured fibers with 23 cores.
  • Analysis of supermode coupling and propagation characteristics.
  • Demonstrated potential for beam shaping and quality enhancement.

Conclusions:

  • Linear-core-array microstructured fibers are a promising platform for high-power fiber lasers.
  • The developed fabrication and analysis methods provide insights into controlling light propagation.
  • These fibers can significantly improve laser beam quality.