Related Experiment Video
Updated: Jun 22, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
Multidetector computed tomography findings in deaths with severe burns
Angela D Levy1, Howard T Harcke, John M Getz
1Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. alevy@usuhs.mil
Postmortem multidetector computed tomography (MDCT) effectively identifies thermal injuries in charred remains. Autopsy, however, is crucial for determining fire as a cause of death, especially with elevated carboxyhemoglobin levels.
Area of Science:
- Forensic pathology
- Radiology
- Toxicology
Background:
- Charred remains present unique challenges in forensic investigations.
- Determining cause and manner of death requires specialized techniques.
Purpose of the Study:
- To compare postmortem multidetector computed tomography (MDCT) findings with autopsy results in charred human remains.
- To evaluate the utility of MDCT as a complementary tool to autopsy in fire-related fatalities.
Main Methods:
- Seventeen male subjects with charred remains underwent total body MDCT prior to autopsy.
- Autopsy included serum carboxyhemoglobin measurement.
- MDCT findings were correlated with autopsy observations.
Main Results:
- MDCT accurately depicted all thermal tissue alterations and lethal fracture patterns.
- Autopsy identified fire as a contributory cause of death when carboxyhemoglobin was elevated.
- MDCT showed limitations in detecting lethal vascular and visceral injuries.
Conclusions:
- MDCT is a valuable adjunct to autopsy for charred remains, enhancing limited autopsies.
- This approach is particularly beneficial in mass casualty incidents involving fire victims.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies III: Computed Tomography

