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Related Concept Videos

Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Complementation Tests00:49

Complementation Tests

A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Dihybrid Crosses01:18

Dihybrid Crosses

Overview
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...

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Related Experiment Video

Updated: Jun 22, 2026

In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth
06:38

In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth

Published on: September 20, 2021

Mapping quantitative trait loci regulating chicken body composition traits.

Y Gao1, Z Q Du, W H Wei

  • 1State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.

Animal Genetics
|May 27, 2009
PubMed
Summary
This summary is machine-generated.

This study identified 21 quantitative trait loci (QTL) influencing chicken body composition in an F2 population. Significant QTLs were found on GGA1 and GGA5, suggesting potential pleiotropic effects for body composition traits.

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Area of Science:

  • Animal Genetics
  • Quantitative Genetics
  • Poultry Science

Background:

  • Understanding genetic control of body composition is crucial for poultry breeding.
  • Previous studies have identified quantitative trait loci (QTL) for various chicken traits.

Purpose of the Study:

  • To detect QTL affecting chicken body composition traits using an F2 resource population.
  • To investigate potential pleiotropic effects of identified QTL.

Main Methods:

  • Genome scans were performed on an F2 population derived from White Plymouth Rock and Silkie Fowl.
  • 129 microsatellite markers were used for genotyping 238 F2 individuals.
  • 12 body composition traits were phenotyped, including proventriculus weight and shank girth.

Main Results:

  • A total of 21 genome-wide QTL were identified, influencing 11 different body composition traits.
  • Three QTL were genome-wide significant: two on GGA1 and one on GGA5.
  • QTL on GGA1 showed potential pleiotropic effects on gizzard weight, shank girth, and intestine length.

Conclusions:

  • The identified QTL, particularly on GGA1 and GGA5, contribute to the genetic architecture of chicken body composition.
  • Further research is recommended to elucidate the pleiotropic roles of QTL on GGA1 and GGA5 for shank-related traits.