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Updated: Jun 22, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
[Primary application of identification-aided system for diagnosis and differential diagnosis of emerging infectious
Ye-dong Wang1, Shao-li You, Bao-sen Li
1The No. 302 Hospital of the Chinese People's Liberation Army, Beijing 100039, China.
Objective:
To verify the rate of diagnostic fitting between the clinic and the indentification-aided for diagnosis and differential diagnosis system, for emerging infections diseases (EID) established.
Methods:
314 cases of 49 kinds of contagious diseases diagnosed and another 186 patients with fever who not diagnosed were tested by the system.
Results:
Preliminary verification was made in 314 cases diagnosed which classified to 49 kinds of contagious diseases of infectious diseases and the results showed that the coincidence rate of clinical diagnosis and first diagnosis of this system was 61.9%; the suggestive rate of first three diagnoses was 78.1%, and that of first five diagnoses was 86.6%. The diagnosis of another 186 patients with fever were diagnosed by the system and the results showed that the coincidence rate of clinical diagnosis and first diagnosis was 59.7%; the suggestive rate of first three diagnoses was 77.9%, and that of first five diagnoses was 85.4%.
Conclusions:
The system can accurately suggest impossible diagnosis and differential diagnosis, and be useful for our medical work.
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