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Transgeneration effects of antenatal acute hypoxia during early organogenesis

T Yu Dunaeva1, L K Trofimova, A V Graf

  • 1Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Russia. connie-phys@mail.ru

Bulletin of Experimental Biology and Medicine
|June 4, 2009
PubMed

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Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...