Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence and Consensus Based Guidelines for Imaging in Tubercular Choroiditis. Multimodal imaging in Uveitis (MUV) Taskforce: Report 17.

Ophthalmology. Retina·2026
Same author

Emerging therapeutic targets in non-infectious uveitis and scleritis.

Frontiers in medicine·2026
Same author

Evidence and Consensus-Based Guidelines in Vogt-Koyanagi-Harada Disease. Multimodal Imaging in Uveitis (MUV) Taskforce Report 16.

Ophthalmology. Retina·2026
Same author

Exudative Diabetic-Radiation Retinopathy with Lipemia Retinalis Mimicking Cytomegalovirus Retinitis.

Retinal cases & brief reports·2026
Same author

Maribavir for cytomegalovirus retinitis: A case series and review of the literature.

AJO international·2026
Same author

Balancing Vision and Cancer Treatment: Perspectives on Modern Cancer Therapeutics and the Eye.

Clinical & experimental ophthalmology·2026
Same journal

Is ophthalmology a pain-free career? A systematic review and meta-analysis of musculoskeletal pain among ophthalmologists.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same journal

Evaluation of the Deep Reality Viewer for teaching slit-lamp examination of the anterior segment and the optic nerve head.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same journal

Sequential anterior ischaemic optic neuropathy associated with angioid streaks and sphenoid fibrous dysplasia.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same journal

Comparative risk of glaucoma surgery in uveitis-associated versus primary open-angle glaucoma: a multicentre database study.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same journal

Childhood overweight and obesity as risk factors for astigmatism: a longitudinal analysis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same journal

Stage 1 IRVAN syndrome in an asymptomatic female with BRIP1 mutation.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Persistent pupillary dilation in herpes simplex uveitis.

Debra A Goldstein1, Andrew A Mis, Frederick S Oh

  • 1University of Illinois at Chicago Eye and Ear Infirmary, 60612-7243, USA. debrgold@uic.edu

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|June 4, 2009
PubMed
Summary
This summary is machine-generated.

Herpes simplex virus (HSV) infection is linked to iris atrophy and pupillary dilation in patients with unexplained uveitis. This finding aids in diagnosing HSV keratouveitis.

More Related Videos

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
07:55

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection

Published on: November 3, 2012

Related Experiment Videos

Last Updated: Jun 22, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
07:55

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection

Published on: November 3, 2012

Area of Science:

  • Ophthalmology
  • Virology
  • Immunology

Background:

  • Herpes simplex virus (HSV) is a common cause of infectious eye disease.
  • Anterior uveitis can present with various clinical signs, sometimes making diagnosis challenging.

Purpose of the Study:

  • To investigate the association between herpes simplex virus (HSV) and specific ocular findings.
  • To determine if iris atrophy and pupillary dilation are indicative of HSV infection in uveitis cases.

Main Methods:

  • A retrospective case series design was employed.
  • Data from 13 patients diagnosed with HSV keratouveitis were analyzed.
  • Ophthalmologic evaluations focused on iris detail and pupillary size.

Main Results:

  • All 13 patients exhibited some degree of iris atrophy.
  • Nine out of 13 patients showed pupillary dilation on the affected side without the use of dilating drops.

Conclusions:

  • Iris atrophy and unexplained pupillary dilation are significant clinical indicators.
  • These findings suggest a diagnosis of herpes simplex virus (HSV) keratouveitis in patients with anterior uveitis.