Related Experiment Video
Updated: Jun 22, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
Published on: May 22, 2026
[Psychopharmacotherapy of the elderly]
M Axel Wollmer1, Franz Müller-Spahn
1Universitäre Psychiatrische Kliniken Basel, Basel. marcaxel.wollmer@upkbs.ch
Abstract:
Pharmacokinetic and pharmacodynamic changes related to aging and age-associated disorders influence the choice and dosage of psychotropic drugs in the treatment of the elderly. Renal and hepatic clearance is limited and the sensitivity to pharmacological effects is increased. To avoid side effects most psychotropic drugs should be introduced in a 'start low--go slow' approach. The final dose may also be lower than in the treatment of younger adults. Drug interactions may occur as a consequence of a complex medication. Peculiarities of the treatment of older adults with antidepressants, antipsychotics, anxiolytics, mood-stabilizers and hypnotics is described.
Related Concept Videos
Drug Dosing: Geriatric Patients
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Psychosis: Goals of Pharmacotherapy
