Related Experiment Video
Updated: Jun 22, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Molecular dynamics of some pentapeptides having a strong tendency to helical conformation
Zhuo-Ran Huang1, Tong-Yang Zhu, Ting-Ting Wang
1State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing 210093, China.
Abstract:
Some pentapeptides with higher alpha-helical tendency possess typical sequence pattern, such as "+ - + + - - +", "+ - - + - - +", "+ - + - - - +", and " - + + - - - +" ( "+" = D,N,E,Q,K,R,T,C, or H; "-" = L,I,V, or A), especially symmetrical motifs (a pair of reverse sequences beside palindromic segments), such as ALALA, QQAQE/EQAQQ, and REALE/ELAER, hint that the nascent peptide can fold a certain conformation in a two-way folding fashion.
Related Concept Videos
Protein Folding
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
Protein Folding
Protein Organization
Protein Organization
The primary structure of a protein is its amino acid sequence.
Molecular Chaperones and Protein Folding
The...
Protein and Protein Structure
A protein's shape is critical to its function. For example, an enzyme can...

