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Updated: Jun 22, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
[Late stent thrombosis]
Milovan Petrović1, Miroslav Bikicki, Gordana Panić
1Institut za kardiovaskularne bolesti Vojvodine, Sremska Kamenica, Klinika za kardiologiju. nsbim@EUnet.yu
Insights
Late stent thrombosis, a rare but serious complication, can cause heart attack or death. Proper dual antiplatelet therapy and technically correct Percutaneous Coronary Intervention (PCI) are crucial for prevention.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Late stent thrombosis is a severe complication following stent implantation, potentially leading to acute myocardial infarction or death.
- This case report details a patient experiencing recurrent myocardial infarction due to late stent thrombosis in previously implanted bare metal stents.
Observation:
- A 43-year-old male presented with acute ST-elevation myocardial infarction and right ventricular infarction, 18 months after initial Percutaneous Coronary Intervention (PCI) with two bare metal stents.
- Coronarography revealed right coronary artery occlusion at the site of previous stents, with thrombi identified in the stented segments and branches.
- The patient underwent repeat PCI, including guidewire recanalization, thrombus removal, and GP IIb/IIIa antagonist therapy.
Findings:
- Successful recanalization and treatment of thrombi resulted in good anterograde flow after repeat PCI.
- The patient's condition improved post-intervention, with minimal residual artery opacification defects.
Implications:
- This case underscores the critical importance of appropriate dual antiplatelet therapy post-PCI to mitigate the risk of late stent thrombosis.
- Ensuring technically sound PCI procedures, including correct stent sizing and expansion, is vital for long-term stent patency and patient outcomes.
Introduction:
Late stent thrombosis is a serious complication after stent implantation and it can lead to the development of acute myocardial infarction or death.
A Case Report:
A 43-year-old patient was admitted to our clinic to coronary care unit. He was diagnosed with acute ST elevation myocardial reinfarction of inferoposterior localization and with right ventricular myocardial infarction. Eighteen months ago, he had acute myocardial infarction of the same localization, and at the same time, PCI (Percutaneous Coronary Intervention) was performed in acute phase, and two bare metal stents were implanted. Now, the patient had chest discomfort two hours before admittance, and PCI was performed once again in acute phase. The diagnostic coronarography resulted in occlusion of the right coronary artery, on the spot of the previously implanted stents. After the passage of guidewire, the artery was recanalized, and defects of artery opacification, which might have been thrombs, were noticed. The thrombs were seen on the spots of earlier implanted stents and in the posterior inteventricular and posterolateral branches of the right coronary artery. PTCA was performed and the patient received the GP IIb/IIIa antagonist therapy after which the control coronarography showed minimal defects of artery opacification, with good anterograde flow. After complete treatment the patient was in good condition.
Conclusion:
Late stent thrombosis, although not very often, is a very serious complication and can lead to death or acute myocardial infarction. To prevent it, it is necessary that the patient receives dual antiplatelet therapy, and that PCI procedure is performed technically correctly (suitable stent dimensions and proper stent expansion).
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