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Related Experiment Video

Updated: Jun 22, 2026

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

Functional state following the Fontan procedure.

Ismee A Williams1, Lynn A Sleeper, Steven D Colan

  • 1Department of Pediatrics, Division of Cardiology, Columbia University Medical Centre, New York, New York, USA. iib6@columbia.edu

Cardiology in the Young
|June 16, 2009
PubMed
Summary
This summary is machine-generated.

Long-term functional outcomes after Fontan circulation are influenced by pre-operative factors like right ventricular morphology and oxygen saturation, as well as post-operative arrhythmias and socioeconomic status. These characteristics help predict overall patient function.

Related Experiment Videos

Last Updated: Jun 22, 2026

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease
  • Fontan Circulation Outcomes

Background:

  • Outcomes after Fontan circulation have improved, but long-term functional status remains variable.
  • Identifying factors influencing long-term function is crucial for patient management.

Purpose of the Study:

  • To identify pre- and postoperative characteristics associated with overall functional state in survivors of Fontan circulation.

Main Methods:

  • A functional score was calculated for 476 survivors using ventricular ejection fraction, maximal oxygen consumption, Child Health Questionnaire physical summary score, and brain natriuretic peptide levels.
  • Statistical analysis adjusted for time since Fontan completion to identify associated factors.

Main Results:

  • Worse functional state was associated with right ventricular morphology, higher ventricular end-diastolic pressure, and lower pre-operative oxygen saturation.
  • Lower caregiver income and post-operative arrhythmias (in select patients) were also linked to poorer function.
  • The model explained 18% of the variation in functional scores; factors like surgical center and sex were not associated.

Conclusions:

  • Pre-operative ventricular characteristics, oxygen saturation, socioeconomic status, and post-operative arrhythmias are significant predictors of long-term functional state after Fontan circulation.
  • Unidentified factors also play a role in determining functional outcomes.