Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

634
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
634
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

550
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
550
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

506
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
506
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

1.7K
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
1.7K
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

379
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
379
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

413
Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
413

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hypertension in Children: Narrative Review of Epidemiology, Outcome and Target Organ Damage.

Children (Basel, Switzerland)·2026
Same author

Exploring Mixed Feeding Practices Among Indian Mothers: Knowledge, Attitudes, and Reported Barriers to Exclusive Breastfeeding.

Cureus·2026
Same author

Health Care Utilization in Adults With Congenital Heart Disease: Population-Based Findings.

Birth defects research·2026
Same author

The state of metabolic engineering in the versatile bacterial cell factory Cupriavidus necator H16.

Metabolic engineering·2026
Same author

Double bridge to heart transplantation: Outcomes of early versus delayed extracorporeal membrane oxygenation crossover in pediatric population.

JTCVS open·2026
Same author

A practical approach to ABO-incompatible heart transplantation from the Pediatric Heart Transplant Society (PHTS).

JHLT open·2026
Same journal

Cardiac Imaging Predictors of Ventricular Recovery in Pediatric Patients Undergoing Aortic Valve Intervention for Regurgitation.

Pediatric cardiology·2026
Same journal

Holter-Based Heart Rate Variability Distinguishes Adolescent Postural Orthostatic Tachycardia Syndrome from Healthy Controls.

Pediatric cardiology·2026
Same journal

Left Atrial Function in Children with Cancer Prior to Start of Chemotherapy: A Speckle Echocardiography Analysis.

Pediatric cardiology·2026
Same journal

Early Improvement in Cardiac Autonomic Modulation After a Recreational Physical Training Program in Healthy Children.

Pediatric cardiology·2026
Same journal

Beyond Body Mass Index: Skeletal Muscle Mass as a Marker of Physiologic Reserve in Fontan Circulation.

Pediatric cardiology·2026
Same journal

Geographical and Language-Based Factors Associated with Neurodevelopmental Follow-Up in Children with Congenital Heart Disease.

Pediatric cardiology·2026
See all related articles

Related Experiment Video

Updated: Feb 22, 2026

Assessing Functional Performance in the Mdx Mouse Model
10:32

Assessing Functional Performance in the Mdx Mouse Model

Published on: March 27, 2014

33.9K

Cardiac Performance Evaluation in Patients with Muscular Dystrophy.

Naomi Khanna1, Joseph Mahgerefteh2, Noah Elkins3

  • 1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.

Pediatric Cardiology
|February 20, 2026
PubMed
Summary
This summary is machine-generated.

Ventriculoarterial coupling (VAC) is impaired in muscular dystrophy (MD) patients and worsens over time. Reduced cardiac function in MD is linked to ambulation status, offering insights into disease progression.

Keywords:
Cardiac functionEchocardiogramMuscular dystrophy

More Related Videos

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
14:10

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies

Published on: January 31, 2013

34.0K
Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

10.9K

Related Experiment Videos

Last Updated: Feb 22, 2026

Assessing Functional Performance in the Mdx Mouse Model
10:32

Assessing Functional Performance in the Mdx Mouse Model

Published on: March 27, 2014

33.9K
Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
14:10

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies

Published on: January 31, 2013

34.0K
Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

10.9K

Area of Science:

  • Cardiology
  • Neuromuscular Disorders
  • Biomedical Engineering

Background:

  • Ventriculoarterial coupling (VAC) assesses the relationship between ventricular performance and arterial stiffness.
  • Muscular dystrophy (MD) is associated with various systemic complications, including cardiac involvement.

Purpose of the Study:

  • To investigate if VAC is abnormal in muscular dystrophy (MD) patients.
  • To determine if VAC worsens with disease progression in MD.
  • To identify factors associated with abnormal VAC in MD.

Main Methods:

  • Echocardiograms were used to calculate arterial elastance (Ea) and LV end-systolic elastance (Ees) in MD patients and controls.
  • VAC was compared between initial and follow-up studies in MD patients.
  • Regression analyses identified factors associated with VAC.

Main Results:

  • MD patients exhibited significantly lower ejection fraction (EF) and Ees, and a higher VAC ratio compared to controls.
  • Cardiac dysfunction worsened over the follow-up period in MD patients.
  • Ambulation status was independently associated with EF and Ees at last follow-up.

Conclusions:

  • Cardiac performance, measured by VAC, is impaired in MD patients and deteriorates longitudinally.
  • Ambulation status is a key factor associated with cardiac dysfunction in MD.
  • Findings provide mechanistic insights into cardiac dysfunction progression in MD.