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Updated: Jun 22, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Ultra-high-speed optical coherence tomography with a stretched pulse supercontinuum source.
We developed a novel high-speed Fourier-domain optical coherence tomography (FD-OCT) system using a stretched pulse supercontinuum laser. This advanced technique achieves an ultrahigh axial-line scanning rate of 5 MHz with 8-micrometer resolution.
Area of Science:
- Biomedical Optics
- Optical Imaging
- Metrology
Background:
- Fourier-domain optical coherence tomography (FD-OCT) is a powerful non-invasive imaging technique.
- Achieving higher imaging speeds in FD-OCT is crucial for real-time applications and reducing motion artifacts.
- Existing high-speed FD-OCT methods often require complex setups or active wavelength tuning.
Purpose of the Study:
- To introduce a new, simplified high-speed FD-OCT scheme.
- To demonstrate an ultrahigh axial-line scanning rate using a novel light source.
- To achieve high axial resolution without active sweep re-calibration.
Main Methods:
- Utilized a supercontinuum source generating a wide spectrum (1,200-1,550 nm).
- Employed group-velocity dispersion in a fiber to stretch short pulses into 70-ns long pulses.
- Acquired spectral interferograms in the time domain and converted them to the spectral domain using a pre-calibrated time-to-wavelength relation.
- Implemented the stretched-pulse OCT (SP-OCT) scheme.
Main Results:
- Demonstrated an ultrahigh axial-line scanning rate of 5 MHz.
- Achieved an axial resolution of 8 micrometers.
- The frequency-sweeping mechanism was passive, eliminating the need for re-calibration.
Conclusions:
- The stretched-pulse OCT (SP-OCT) scheme offers a simplified approach to ultrahigh-speed FD-OCT.
- This method enables high-speed imaging with excellent axial resolution.
- The passive nature of the frequency-sweeping mechanism enhances system stability and ease of use.
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