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Study of the cognitive component of nociception by the tail flick method

E V Nikenina1, Yu B Abramov

  • 1P. K. Anokhin Institute of Physiology, Russian Academy of Medical Sciences, Moscow, Russia. nikenina@mail.ru

Bulletin of Experimental Biology and Medicine
|June 17, 2009
PubMed

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Nociception01:44

Nociception

Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain. Thus, pain helps the...