[The morphological characteristics of the endocervicoses in genital herpes]

Uterine cervix biopsies from 450 patients with endocervicosis were studied morphologically. Giant cell metamorphosis, nuclei hypertrophy and hyperchromatism with intranuclear viral basophilic inclusions typical for herpes infection were found in 24 cases (5.3%). These cell alterations were mainly observed in squamous epithelium of the uterine cervix, columnar epithelium of the glands and to a lesser degree in the stromal fibroblasts and vascular endothelium. These morphological changes were confirmed in 6 of 10 cases by means of the fluorescent antibodies to the herpes simplex viral antigen.